Different Region Explanation
The different region signify where the game is being made for R1 = US | R2 = Europe | R3 = Asia (MY/HK/SG/TH/ID/PH) | R4 = Australia & Oceania
There is no difference in the gameplay. However, different regions may or may not have the same:
Box Art | Downloadable Contents (DLC) | Voiceovers & Subtitles | Online Servers | Pricing
If you do not play online or just want to play the game itself, region does not matter. Just buy the cheapest version!
If you have preference between DLC/Cover/Languages, please do more research as it varies from game to game!
Tips For Multiple Region PSN Account
For Multiple Psn Account user , Please Activate all your psn account to primary account
then you will able to access diffrent region acount dlc with your Favorite (MY) PSN ACCOUNT